Pedunculated Hepatocellular Adenoma: A Presentation of a Rare Disease A report of Two Cases with Review of Literature Faris Izzideen Khiro* FICMS EBP, Hasanain Abdulameer Jasim** FICS CABS

  • imj Iraq Medical Journal
Keywords: Liver cell adenoma, Liver tumors, Contraceptive pills.


Background: Liver cell adenomas are rare tumors of the liver that shows increased incidence in some circumstances, as the peculiar increase in incidence with the use of contraceptive drugs in females of child-bearing age, or idiopathic. These tumors carry the risk to transform to hepatocellular carcinoma. Grossly, these tumors usually present as a single or more tumor masses and rarely present as a pedunculated mass. Recent histological, immunohistochemical and molecular studies conclude distinct patterns with clear prognostic implications. Case presentation: We present two cases of liver cell adenoma, both in young adult females with history of contraceptive pill use for some years, both cases presented as single large pedunculated liver tumors. Both tumors were resected completely and successfully. Both cases showed typical histological picture of liver cell adenoma with prominent fatty infiltration 'Steatotic subtype'. Conclusion: Liver cell adenomas can are rare tumors that can be precancerous in some of the cases.


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