Assessment of Ovarian Reserve by Hormonal and Ultrasound Markers among Fertile and Infertile Women Ban Hadi Hameed* FICOG, Shaymaa Abdul Sattar Nayyef** FICOG, Yasmin Najim Abdulla** DGO, Miami Abdul Hassan Ali* FICOG
Background: Infertility of an ovarian origin is one of the most distressing conditions to both the gynecologist and the partners which necessitate the use of markers that can predict the ovarian reserve and the response for infertility treatment.
Objective: To assess the ovarian reserve in the infertile women by means of hormonal and ultrasound markers and compare them with fertile women.
Methods: A prospective case control study was carried out on 60 infertile women (study group) and 60 healthy fertile women (control group) for a period of one year from January 2012 till January 2013 at Al Yarmouk teaching hospital in Baghdad. We compared the ultrasound and hormonal markers as predictors of ovarian reserve in both groups.
Results: The mean serum inhibin B level was lower in the study group in comparison to the control group. The difference was statistically significant. There was no significant difference in the mean serum estradiol level in the study group in comparison to the control group. The mean serum follicle stimulating hormone level was significantly higher in the study group. The ovarian volume was larger in the control group than the study group. The difference was statistically significant. The mean number of large size antral follicles was significantly higher in the control group than the study group. The mean number of small size antral follicles was significantly higher in the control group than the study group.
Conclusion: This study suggests that higher number of the small size antral follicles, higher serum inhibin B and lower serum follicle stimulating hormone might be considered as good predictors of ovarian reserve.
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