Sonographic Myometrial Thickness for Prediction of Latency Interval in Preterm Premature Rupture of Membrane Shatha Sami Hussein* FICOG CABOG, Manal Madany Abdulqadar* FICOG CABOG, Ekhlass Hussam Sabri Al-Rawi** FICOG CABOG

Keywords: Myometrial thickness, Preterm premature rupture of membrane, Latency period, Prematurity, Oligohydramnios


Background: Preterm labor still a main complication that may occur to the normal pregnancy in the presence of many risk factors and can lead to several health problems for both fetus and mother. Much effort done to prevent and decrease these complications.
Objective: To detect if measurement of myometrial thickness can be used to predict latency interval in preterm premature rupture of membrane.
Methods: Analytic-descriptive and case-control study conducted at Al-Yarmouk teaching hospital from the 1st of January, 2016 to the 1st of January 2017. Sixty pregnant women with gestational age from 28+0 - 40+6 weeks were involved in the study and were divided into two groups: (Group A) 30 pregnant women with PPROM, the case group, and (Group B) 30 term healthy pregnant women as control group. Amniotic membrane rupture was diagnosed by both speculum examination, and ultrasound proved the presence of oligohydramnios. Trans-abdominal ultrasound done for all patients by the same expert sonographist to measure the myometrial thickness at posterior, anterior and fundal uterine wall and amniotic fluid index. The interval from ultrasound time until delivery was calculated for all patient and result compared statistically.
Results: Descriptive analysis data between two groups revealed no significant differences regarding age, gravid, parity, while there was significant difference regarding gestational age P-value 0.0001. The difference between myometrial thicknesses between the two groups revealed that the mean of myometrial thickness in the mid anterior part of uterus was 10.64±0.60mm in preterm premature rupture of membrane group compared with 8.81±1.34 mm in group B (P-value 0.001). The mean of fundal myometrial thickness in group A was 11.23±0.88 compared with 8.41±1.12 in group B which was statistically significant (P-value 0.0001). The posterior myometrial was thicker in group A than group B. No significant relation with labor time and myometrial thickness in both studying group , p value were 0.062,0.061,0.776 for mid-anterior, fundal, posterior walls respectively in group A, while it was 0.443,0.191,0.475 for mid-anterior, fundal, posterior walls respectively in group B.
Conclusion: There was no significant correlation was found between myometrial thickness in fundal, anterior and posterior walls with latency period.