Assessment of Antimicrobial Susc Assessment of Antimicrobial Susceptibility Patterns in Urine Culture of Patients with Urinary Tract Infection Attending AlKindy Teaching Hospital Saad Baddai Nashtar* PhD
Background: Urinary tract Infection is a common and serious health problem affecting millions of people each year around the World, especially females. Urinary tract infection treatment relies on the predictability of the causative agents and knowledge of their antimicrobial susceptibility patterns.
Objectives: To identify the bacterial species causing urinary tract Infection in Iraqi patients and to assess microbial susceptibility towards the commonly used antimicrobials.
Methods: This prospective, observational study was conducted in Al-Kindy teaching hospital. Urine culture and susceptibility reports of 168 urinary tract Infections outpatients collected for one year (2016), the number and percentage of the isolated microorganisms was recorded then the percentage of susceptibility of all these pathogens toward each of the used antimicrobials was calculated.
Results: It was found that E coli was the most common bacteria isolated (48.8%) followed by klebsiella (11.3%) and enterococcus fecalis (8.33%). The most susceptible antimicrobials were carbapenem (95.8%), amikacin (86.8%), nitrofurantoin (80%) and gentamycin (77.4%). Ampicillin and trimethprim were the less susceptible (16.7% and 16.8%, respectively). Second-generation cephalosporin, cephalothin also showed weak susceptibility (23.3%) while third generation ceftriaxon and cefotaxime have shown a better effect (60.9 and 73.1%), respectively.
Conclusion: Although treatment of urinary tract Infection better follow culture and sensitivity test, aminoglycosides or third generation cepaholsporins with nitrofurantoin are the best combination. Ampicillin, amoxicillin and trimethoprim are better avoided. It is better to preserve carbapenem for the resistant cases
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